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Cognitive performance (MTAG)

CYB561D1 · rs6666119

Where this position leads

Condition: Educational Attainment

rs6666119 Condition: Educational Attainment Educational Attainment Condition rs6666119 rs6666119 CYB561D1

What the study found

Who was studied 402,382 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0235 lower (95% confidence interval 0.019-0.028); p = 3 × 10−21.

How common The A allele had a frequency of about 69% in the people studied.

Where it sits Chromosome 1, band 1p13.3 — in the 3′ untranslated region of CYB561D1.

What each result means

A/A Two copies of the version the research linked to Cognitive performance (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Cognitive performance (MTAG). That is a smaller link than two copies.
G/G No copy of the version the research linked to Cognitive performance (MTAG). This is the starting point the study compared everyone against.
Source

Questions about rs6666119

What is rs6666119?

rs6666119 is a single position in the genome, in or near the CYB561D1 gene. Published research associates it with cognitive performance (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6666119 linked to?

On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.

Does having rs6666119 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6666119 come from?

GWAS Catalog, Nature genetics 2018, PMID:30038396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Cognitive performance (MTAG) (rs6666119). MyGeneLog™. https://www.mygenelog.com/variants/rs6666119

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