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RB11B protein level (protein group normalized intensity)

near CFHR1 · rs6665824

What the study found

Who was studied 1,205 European, Hispanic or African ancestry individuals; replicated in 325 Arab, Indian or Filipino ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.243 lower (95% confidence interval 0.17-0.32); p = 8 × 10−11.

How common The A allele had a frequency of about 44% in the people studied.

Where it sits Chromosome 1, band 1q31.3 — between genes, 13.9 kb from CFHR1.

What each result means

A/A Two copies of the version the research linked to RB11B protein level (protein group normalized intensity). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to RB11B protein level (protein group normalized intensity). That is a smaller link than two copies.
C/C No copy of the version the research linked to RB11B protein level (protein group normalized intensity). This is the starting point the study compared everyone against.
Source

Questions about rs6665824

What is rs6665824?

rs6665824 is a single position in the genome, in or near the near CFHR1 gene. Published research associates it with rb11b protein level (protein group normalized intensity). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6665824 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6665824 come from?

GWAS Catalog, Nature genetics 2025, PMID:41310232. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

RB11B protein level (protein group normalized intensity) (rs6665824). MyGeneLog™. https://www.mygenelog.com/variants/rs6665824

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