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Alcohol dehydrogenase [NADP(+)] levels

GPBP1L1 · rs6662572

What the study found

Who was studied 997 European ancestry individuals; replicated in 338 Greater Middle Eastern (Middle Eastern, North African or Persian), South Asian ancestry, Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.326 lower (95% confidence interval 0.23-0.42); p = 6 × 10−11.

Where it sits Chromosome 1, band 1p34.1 — in an intron of GPBP1L1.

What each result means

A/A No copy of the version the research linked to Alcohol dehydrogenase [NADP(+)] levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Alcohol dehydrogenase [NADP(+)] levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Alcohol dehydrogenase [NADP(+)] levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6662572

What is rs6662572?

rs6662572 is a single position in the genome, in or near the GPBP1L1 gene. Published research associates it with alcohol dehydrogenase [nadp(+)] levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6662572 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6662572 come from?

GWAS Catalog, Nature communications 2017, PMID:28240269. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Alcohol dehydrogenase [NADP(+)] levels (rs6662572). MyGeneLog™. https://www.mygenelog.com/variants/rs6662572

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