TRIB1AL · rs66614050
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 28,037 African American or Afro-Caribbean cases, 27,468 African American or Afro-Caribbean controls, 14,887 Hispanic or Latin American cases, 14,427 Hispanic or Latin American controls, 1,998 East Asian ancestry cases, 1,549 East Asian ancestry controls, 176,604 European ancestry cases, 139,064 European ancestry controls.
The effect Each copy of the C allele shifted the measure 0.119 higher (95% confidence interval 0.11-0.13); p = 2 × 10−119.
How common The C allele had a frequency of about 57% in the people studied.
Where it sits Chromosome 8, band 8q24.13 — in an intron of TRIB1AL.
rs66614050 is a single position in the genome, in or near the TRIB1AL gene. Published research associates it with high cholesterol. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
High cholesterol (rs66614050). MyGeneLog™. https://www.mygenelog.com/variants/rs66614050