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Fc receptor-like protein 6 levels

FCRL6 · rs6657365

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 10,708 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.219 higher (95% confidence interval 0.19-0.25); p = 2 × 10⁻³⁸.

How common The C allele had a frequency of about 81% in the people studied.

Where it sits Chromosome 1, band 1q23.2 — in an intron of FCRL6.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Fc receptor-like protein 6 levels compared to the general population.

C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Fc receptor-like protein 6 levels.

G/G Published research associates this genotype with typical/baseline likelihood of Fc receptor-like protein 6 levels — no copies of the reported risk allele.

Source

Mapping the proteo-genomic convergence of human diseases

Pietzner M, Wheeler E, Carrasco-Zanini J, Cortes A, Koprulu M, Wörheide MA, Oerton E, Cook J, Stewart ID, Kerrison ND, Luan J, Raffler J

and 9 more — show all

Arnold M, Arlt W, O'Rahilly S, Kastenmüller G, Gamazon ER, Hingorani AD, Scott RA, Wareham NJ, Langenberg C

Science (New York, N.Y.) · 2021 · PMID 34648354

Questions about rs6657365

What is rs6657365?

rs6657365 is a single position in the genome, in or near the FCRL6 gene. Published research associates it with fc receptor-like protein 6 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6657365 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6657365 come from?

GWAS Catalog, Science (New York, N.Y.) 2021, PMID:34648354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Fc receptor-like protein 6 levels (rs6657365). MyGeneLog™. https://www.mygenelog.com/variants/rs6657365

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