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Acute pancreatitis

RNF128 · rs66491909

Where this position leads

Condition: Acute Pancreatitis

rs66491909 Condition: Acute Pancreatitis Acute Pancreatitis Condition rs66491909 rs66491909 RNF128

What the study found

Who was studied 10,630 European ancestry cases, 844,679 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.0841 higher (95% confidence interval 0.059-0.109); p = 8 × 10−11.

How common The A allele had a frequency of about 25% in the people studied.

Where it sits Chromosome X, band Xq22.3 — in an intron of RNF128.

What each result means

A/A Two copies of the version the research linked to Acute pancreatitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Acute pancreatitis. That is a smaller link than two copies.
G/G No copy of the version the research linked to Acute pancreatitis. This is the starting point the study compared everyone against.
Source

Questions about rs66491909

What is rs66491909?

rs66491909 is a single position in the genome, in or near the RNF128 gene. Published research associates it with acute pancreatitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs66491909 linked to?

On MyGeneLog this position is linked to Acute Pancreatitis. The research behind each link, and its sources, are set out on that condition page.

Does having rs66491909 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs66491909 come from?

GWAS Catalog, Gastroenterology 2023, PMID:36736436. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Acute pancreatitis (rs66491909). MyGeneLog™. https://www.mygenelog.com/variants/rs66491909

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