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Who was studied 402,382 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0162 higher (95% confidence interval 0.011-0.021); p = 2 × 10−10.
How common The T allele had a frequency of about 71% in the people studied.
Where it sits Chromosome 13, band 13q21.31 — in an intron of LINC00358.
What each result means
C/CNo copy of the version the research linked to Cognitive performance (MTAG). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Cognitive performance (MTAG). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Cognitive performance (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
rs66468848 is a single position in the genome, in or near the LINC00358 gene. Published research associates it with cognitive performance (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs66468848 linked to?
On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.
Does having rs66468848 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs66468848 come from?
GWAS Catalog, Nature genetics 2018, PMID:30038396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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