C/CPublished research associates this genotype with typical/baseline likelihood of Lumbar spine bone mineral density — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Lumbar spine bone mineral density.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Lumbar spine bone mineral density compared to the general population.
rs664398 is a single position in the genome, in or near the TMEM135 gene. Published research associates it with lumbar spine bone mineral density. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs664398 linked to?
On MyGeneLog this position is linked to Spine Bone Mineral Density. The research behind each link, and its sources, are set out on that condition page.
Does having rs664398 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs664398 come from?
GWAS Catalog, Bone 2018, PMID:29499414. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.