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Height

BCKDHB · rs660888

Where this position leads

Condition: Height

rs660888 Condition: Height Height Condition rs660888 rs660888 BCKDHB

What the study found

Who was studied 472,730 East Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0282 higher (95% confidence interval 0.023-0.034); p = 3 × 10−24.

How common The A allele had a frequency of about 27% in the people studied.

Where it sits Chromosome 6, band 6q14.1 — in an intron of BCKDHB.

What ClinVar records

Classification Benign; criteria provided, single submitter (1 of 4 stars, 1 submitter), last evaluated 2018-07-31. ClinVar record 1281802 NM_183050.4(BCKDHB):c.1038+274T>A

What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

A/A Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Height. That is a smaller link than two copies.
T/T No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
Source

Questions about rs660888

What is rs660888?

rs660888 is a single position in the genome, in or near the BCKDHB gene. Published research associates it with height. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs660888 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does having rs660888 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs660888 come from?

GWAS Catalog, Nature 2022, PMID:36224396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Height (rs660888). MyGeneLog™. https://www.mygenelog.com/variants/rs660888

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