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C-C motif chemokine 25 levels

near CCL25 · rs6603134

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 997 European ancestry individuals; replicated in 338 Greater Middle Eastern (Middle Eastern, North African or Persian), South Asian ancestry, Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.352 higher (95% confidence interval 0.27-0.44); p = 4 × 10⁻¹⁵.

Where it sits Chromosome 19, band 19p13.2 — between genes, 10.7 kb from CCL25.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of C-C motif chemokine 25 levels compared to the general population.

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with C-C motif chemokine 25 levels.

G/G Published research associates this genotype with typical/baseline likelihood of C-C motif chemokine 25 levels — no copies of the reported risk allele.

Source

Connecting genetic risk to disease end points through the human blood plasma proteome

Suhre K, Arnold M, Bhagwat AM, Cotton RJ, Engelke R, Raffler J, Sarwath H, Thareja G, Wahl A, DeLisle RK, Gold L, Pezer M

and 12 more — show all

Lauc G, El-Din Selim MA, Mook-Kanamori DO, Al-Dous EK, Mohamoud YA, Malek J, Strauch K, Grallert H, Peters A, Kastenmüller G, Gieger C, Graumann J

Nature communications · 2017 · PMID 28240269 · open access

Questions about rs6603134

What is rs6603134?

rs6603134 is a single position in the genome, in or near the near CCL25 gene. Published research associates it with c-c motif chemokine 25 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6603134 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6603134 come from?

GWAS Catalog, Nature communications 2017, PMID:28240269. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

C-C motif chemokine 25 levels (rs6603134). MyGeneLog™. https://www.mygenelog.com/variants/rs6603134

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