Standard

Diacylglycerol (18:0/22:6) (Model 2)

XKR6 · rs6601555

Strength of the evidence

2 / 4

Its strongest genetic-study result is p = 10−32, with 19 associations in the GWAS Catalog.

How this is scored

4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.

What the study found

Who was studied 6,915 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.14 lower; p = 2 × 10−15.

Where it sits Chromosome 8, band 8p23.1 — in a non-coding transcript of XKR6.

How common each version is

CT
Korean KRGDB
C 85.0% · T 14.9%
Korean Korea4K
C 84.7% · T 15.3%
Vietnamese
C 74.1% · T 25.9%
World gnomAD
C 37.2% · T 62.8%
World 1000 Genomes
C 41.8% · T 58.2%
World TOPMed
C 37.2% · T 62.8%

The share of all copies of this position that are each version. Source: the population studies published in dbSNP (US NCBI); each row names its study.

What each result means

C/C No copy of the version the research linked to Diacylglycerol (18:0/22:6) (Model 2). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Diacylglycerol (18:0/22:6) (Model 2). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Diacylglycerol (18:0/22:6) (Model 2). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6601555

What is rs6601555?

rs6601555 is a single position in the genome, in or near the XKR6 gene. Published research associates it with diacylglycerol (18:0/22:6) (model 2). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6601555 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6601555 come from?

GWAS Catalog, Nature communications 2026, PMID:42069741. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Licensed CC BY-NC 4.0: free to read, share and adapt for non-commercial use, naming MyGeneLog™ and linking the exact page. Commercial use, including training or serving a commercial AI system, needs a licence — https://www.mygenelog.com/license

Diacylglycerol (18:0/22:6) (Model 2) (rs6601555). MyGeneLog™. https://www.mygenelog.com/variants/rs6601555

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