Standard

General factor of neuroticism

ENSG00000254091 · rs6601295

Where this position leads

Condition: Neuroticism

rs6601295 Condition: Neuroticism Neuroticism Condition rs6601295 rs6601295 ENSG00000254…

What the study found

Who was studied 270,059 British ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0102 lower (95% confidence interval 0.0067-0.0136); p = 7 × 10−9.

Where it sits Chromosome 8, band 8p23.1 — in an intron of PPP1R3B-DT.

What each result means

A/A Two copies of the version the research linked to General factor of neuroticism. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to General factor of neuroticism. That is a smaller link than two copies.
G/G No copy of the version the research linked to General factor of neuroticism. This is the starting point the study compared everyone against.
Source

Questions about rs6601295

What is rs6601295?

rs6601295 is a single position in the genome, in or near the ENSG00000254091 gene. Published research associates it with general factor of neuroticism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6601295 linked to?

On MyGeneLog this position is linked to Neuroticism. The research behind each link, and its sources, are set out on that condition page.

Does having rs6601295 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6601295 come from?

GWAS Catalog, Molecular psychiatry 2020, PMID:30867560. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

General factor of neuroticism (rs6601295). MyGeneLog™. https://www.mygenelog.com/variants/rs6601295

← See all variants