Standard

Vitamin D insufficiency

near UGT2B7 · rs6600893

Where this position leads

Condition: Vitamin D Deficiency and the GC Gene

rs6600893 Condition: Vitamin D Deficiency and the GC Gene Vitamin D Deficiency and the GC Gene Condition rs6600893 rs6600893 near UGT2B7

What the study found

Who was studied 35,079 European ancestry cases, 140,898 European ancestry controls.

The effect Each copy of the C allele shifted the measure 0.067 higher (95% confidence interval 0.049-0.085); p = 5 × 10−15.

How common The C allele had a frequency of about 45% in the people studied.

Where it sits Chromosome 4, band 4q13.2 — between genes, 0.2 kb from UGT2B7.

What each result means

C/C Two copies of the version the research linked to Vitamin D insufficiency. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Vitamin D insufficiency. That is a smaller link than two copies.
T/T No copy of the version the research linked to Vitamin D insufficiency. This is the starting point the study compared everyone against.
Source

Questions about rs6600893

What is rs6600893?

rs6600893 is a single position in the genome, in or near the near UGT2B7 gene. Published research associates it with vitamin d insufficiency. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6600893 linked to?

On MyGeneLog this position is linked to Vitamin D Deficiency and the GC Gene. The research behind each link, and its sources, are set out on that condition page.

Does having rs6600893 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6600893 come from?

GWAS Catalog, BMJ nutrition, prevention & health 2021, PMID:34308111. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Vitamin D insufficiency (rs6600893). MyGeneLog™. https://www.mygenelog.com/variants/rs6600893

← See all variants