2 4532117222223Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity1Meta AI7Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others23Total45Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 5,333 European ancestry cases, 12,019 European ancestry controls; replicated in 7,053 cases, 9,007 controls.
The effect
Each copy of the T allele carried 1.16 times the odds of Parkinson's disease (95% confidence interval 1.12-1.20); p = 4 × 10−12.
How common The T allele had a frequency of about 31% in the people studied.
Where it sits Chromosome 4, band 4p16.3 — in an intron of TMEM175.
What each result means
C/CNo copy of the version the research linked to Parkinson's disease. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Parkinson's disease. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Parkinson's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs6599388 is a single position in the genome, in or near the GAK gene. Published research associates it with parkinson's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6599388 linked to?
On MyGeneLog this position is linked to Parkinson's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs6599388 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6599388 come from?
GWAS Catalog, Lancet 2011, PMID:21292315. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 4532117222223Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity1Meta AI7Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others23Total45Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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