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Who was studied 5,304 African American individuals, 13,137 European ancestry individuals, 1,317 Hispanic individuals, 1,439 admixed individuals, 703 Chinese ancestry individuals; replicated in 6,500 African American individuals, 2,451 European ancestry individuals, 2,869 Hispanic individuals.
The effect
Each copy of the T allele shifted the measure 0.528 mmHg higher (95% confidence interval 0.38-0.68); p = 6 × 10−12.
How common The T allele had a frequency of about 27% in the people studied.
Where it sits Chromosome 3, band 3p22.1 — in an intron of ULK4.
What each result means
G/GNo copy of the version the research linked to Diastolic blood pressure (long-term average). This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Diastolic blood pressure (long-term average). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Diastolic blood pressure (long-term average). That is the strongest link of the three results. A link in a study is not a diagnosis.
Scientific reports · 2021 · PMID 33603002 · open access
Questions about rs6599176
What is rs6599176?
rs6599176 is a single position in the genome, in or near the ULK4 gene. Published research associates it with diastolic blood pressure (long-term average). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6599176 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs6599176 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6599176 come from?
GWAS Catalog, Scientific reports 2021, PMID:33603002. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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