Standard

Asthma

RAD50 · rs6596086

Where this position leads

Condition: Asthma

rs6596086 Condition: Asthma Asthma Condition rs6596086 rs6596086 RAD50

What the study found

Who was studied 12,093 African American or Afro-Caribbean cases, 105,134 African American or Afro-Caribbean controls, 5,688 Hispanic or Latin American cases, 52,071 Hispanic or Latin American controls, 609 East Asian ancestry cases, 6,004 East Asian ancestry controls, 36,823 European ancestry cases, 398,278 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0742 lower (95% confidence interval 0.059-0.089); p = 7 × 10−19.

How common The T allele had a frequency of about 72% in the people studied.

Where it sits Chromosome 5, band 5q31.1 — in an intron of RAD50.

What each result means

C/C No copy of the version the research linked to Asthma. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Asthma. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Asthma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6596086

What is rs6596086?

rs6596086 is a single position in the genome, in or near the RAD50 gene. Published research associates it with asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6596086 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs6596086 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6596086 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Asthma (rs6596086). MyGeneLog™. https://www.mygenelog.com/variants/rs6596086

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