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Who was studied 153,950 Korean ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0247 higher (95% confidence interval 0.018-0.031); p = 5 × 10−13.
How common The G allele had a frequency of about 43% in the people studied.
Where it sits Chromosome 11, band 11q22.1 — in an intron of ARHGAP42.
What each result means
A/ANo copy of the version the research linked to Systolic blood pressure. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Systolic blood pressure. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Systolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2025 · PMID 40436827 · open access
Questions about rs6590820
What is rs6590820?
rs6590820 is a single position in the genome, in or near the ARHGAP42 gene. Published research associates it with systolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6590820 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs6590820 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6590820 come from?
GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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