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Who was studied 100,453 Chinese Han ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.804 higher (95% confidence interval 0.61-1); p = 2 × 10−16.
How common The T allele had a frequency of about 50% in the people studied.
Where it sits Chromosome 11, band 11q22.1 — between genes, 8.3 kb from PPIAP43.
What each result means
C/CNo copy of the version the research linked to Systolic blood pressure (BMI unadjusted). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Systolic blood pressure (BMI unadjusted). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Systolic blood pressure (BMI unadjusted). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2024 · PMID 39048560 · open access
Questions about rs6590805
What is rs6590805?
rs6590805 is a single position in the genome, in or near the near PPIAP43 gene. Published research associates it with systolic blood pressure (bmi unadjusted). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6590805 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs6590805 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6590805 come from?
GWAS Catalog, Nature communications 2024, PMID:39048560. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 211122114Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others14Total21Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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