Standard

Proprotein convertase subtilisin/kexin type 7 levels

near LINC02702 · rs6589557

What the study found

Who was studied 2,935 Qatari ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.262 lower (95% confidence interval 0.21-0.32); p = 3 × 10−20.

How common The T allele had a frequency of about 38% in the people studied.

Where it sits Chromosome 11, band 11q23.3 — between genes, 8.7 kb from LINC02702.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Proprotein convertase subtilisin/kexin type 7 levels — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Proprotein convertase subtilisin/kexin type 7 levels.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Proprotein convertase subtilisin/kexin type 7 levels compared to the general population.
Source

Questions about rs6589557

What is rs6589557?

rs6589557 is a single position in the genome, in or near the near LINC02702 gene. Published research associates it with proprotein convertase subtilisin/kexin type 7 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6589557 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6589557 come from?

GWAS Catalog, Human molecular genetics 2023, PMID:36168886. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Proprotein convertase subtilisin/kexin type 7 levels (rs6589557). MyGeneLog™. https://www.mygenelog.com/variants/rs6589557

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