Standard

Mean arterial pressure (BMI adjusted)

near NHLRC2 · rs6585252

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 100,453 Chinese Han ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.627 higher (95% confidence interval 0.46-0.8); p = 4 × 10⁻¹³.

How common The G allele had a frequency of about 85% in the people studied.

Where it sits Chromosome 10, band 10q25.3 — between genes, 46.7 kb from NHLRC2.

What each result means

C/C No copy of the version the research linked to Mean arterial pressure (BMI adjusted). This is the starting point the study compared everyone against.

C/G One copy of the version the research linked to Mean arterial pressure (BMI adjusted). That is a smaller link than two copies.

G/G Two copies of the version the research linked to Mean arterial pressure (BMI adjusted). That is the strongest link of the three results. A link in a study is not a diagnosis.

Source

Causal relevance of different blood pressure traits on risk of cardiovascular diseases: GWAS and Mendelian randomisation in 100,000 Chinese adults

Pozarickij A, Gan W, Lin K, Clarke R, Fairhurst-Hunter Z, Koido M, Kanai M, Okada Y, Kamatani Y, Bennett D, Du H, Chen Y

and 14 more — show all

Yang L, Avery D, Guo Y, Yu M, Yu C, Schmidt Valle D, Lv J, Chen J, Peto R, Collins R, Li L, Chen Z, Millwood IY, Walters RG

China Kadoorie Biobank Collaborative Group

Nature communications · 2024 · PMID 39048560 · open access

Questions about rs6585252

What is rs6585252?

rs6585252 is a single position in the genome, in or near the near NHLRC2 gene. Published research associates it with mean arterial pressure (bmi adjusted). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6585252 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6585252 come from?

GWAS Catalog, Nature communications 2024, PMID:39048560. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean arterial pressure (BMI adjusted) (rs6585252). MyGeneLog™. https://www.mygenelog.com/variants/rs6585252

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