Sensitive
Sjögren's syndrome
TNIP1 · rs6579837
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
G/G
Published research associates this genotype with typical/baseline likelihood of Sjögren's syndrome — no copies of the reported risk allele.
G/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Sjögren's syndrome.
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Sjögren's syndrome compared to the general population.
Source
Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome
Lessard CJ,
Li H,
Adrianto I,
Ice JA,
Rasmussen A,
Grundahl KM,
Kelly JA,
Dozmorov MG,
Miceli-Richard C,
Bowman S,
Lester S,
Eriksson P
and 48 more — show all
Eloranta ML,
Brun JG,
Gøransson LG,
Harboe E,
Guthridge JM,
Kaufman KM,
Kvarnström M,
Jazebi H,
Cunninghame Graham DS,
Grandits ME,
Nazmul-Hossain AN,
Patel K,
Adler AJ,
Maier-Moore JS,
Farris AD,
Brennan MT,
Lessard JA,
Chodosh J,
Gopalakrishnan R,
Hefner KS,
Houston GD,
Huang AJ,
Hughes PJ,
Lewis DM,
Radfar L,
Rohrer MD,
Stone DU,
Wren JD,
Vyse TJ,
Gaffney PM,
James JA,
Omdal R,
Wahren-Herlenius M,
Illei GG,
Witte T,
Jonsson R,
Rischmueller M,
Rönnblom L,
Nordmark G,
Ng WF,
Mariette X,
Anaya JM,
Rhodus NL,
Segal BM,
Scofield RH,
Montgomery CG,
Harley JB,
Sivils KL
Nature genetics · 2013 · PMID 24097067 · open access
Questions about rs6579837
What is rs6579837?
rs6579837 is a single position in the genome, in or near the TNIP1 gene. Published research associates it with sjögren's syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs6579837 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6579837 come from?
GWAS Catalog, Nat Genet 2013, PMID:24097067. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants