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Neutrophill percentage (UKB data field 30200)

SCML4 · rs6568491

Where this position leads

Condition: Celiac Disease

rs6568491 Condition: Celiac Disease Celiac Disease Condition rs6568491 rs6568491 SCML4

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.021 lower (95% confidence interval 0.016-0.026); p = 6 × 10−16.

How common The T allele had a frequency of about 17% in the people studied.

Where it sits Chromosome 6, band 6q21 — in an intron of SCML4.

What each result means

A/A No copy of the version the research linked to Neutrophill percentage (UKB data field 30200). This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Neutrophill percentage (UKB data field 30200). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Neutrophill percentage (UKB data field 30200). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6568491

What is rs6568491?

rs6568491 is a single position in the genome, in or near the SCML4 gene. Published research associates it with neutrophill percentage (ukb data field 30200). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6568491 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs6568491 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6568491 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Neutrophill percentage (UKB data field 30200) (rs6568491). MyGeneLog™. https://www.mygenelog.com/variants/rs6568491

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