Sensitive

Systemic lupus erythematosus

PRDM1 · rs6568431

Where this position leads

Condition: Systemic Lupus Erythematosus

rs6568431 Condition: Systemic Lupus Erythematosus Systemic Lupus Erythematosus Condition rs6568431 rs6568431 PRDM1

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Systemic lupus erythematosus compared to the general population. (GWAS Catalog, Nat Genet 2015, PMID:26502338)
A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Systemic lupus erythematosus. (GWAS Catalog, Nat Genet 2015, PMID:26502338)
C/C Published research associates this genotype with typical/baseline likelihood of Systemic lupus erythematosus — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2015, PMID:26502338)

Source: GWAS Catalog, Nat Genet 2015, PMID:26502338

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs6568431

What is rs6568431?

rs6568431 is a single position in the genome, in or near the PRDM1 gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6568431 linked to?

On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs6568431?

Subjects that appear in the title or abstract of the same papers as this rsID include infection and immunity (2 papers), liver (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs6568431 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6568431 come from?

GWAS Catalog, Nat Genet 2015, PMID:26502338. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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