Sensitive

Bipolar disorder

TRANK1 · rs6550435

Where this position leads

Condition: Bipolar Disorder

rs6550435 Condition: Bipolar Disorder Bipolar Disorder Condition rs6550435 rs6550435 TRANK1

What the study found

Who was studied 9,747 European ancestry cases, 14,278 European ancestry controls.

The effect Each copy of the G allele carried 1.13 times the odds of Bipolar disorder; p = 2 × 10−8.

Where it sits Chromosome 3, band 3p22.2 — between genes, 0.5 kb from LINC02033.

What each result means

G/G Two copies of the version the research linked to Bipolar disorder. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Bipolar disorder. That is a smaller link than two copies.
T/T No copy of the version the research linked to Bipolar disorder. This is the starting point the study compared everyone against.
Source

Questions about rs6550435

What is rs6550435?

rs6550435 is a single position in the genome, in or near the TRANK1 gene. Published research associates it with bipolar disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6550435 linked to?

On MyGeneLog this position is linked to Bipolar Disorder. The research behind each link, and its sources, are set out on that condition page.

Does having rs6550435 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6550435 come from?

GWAS Catalog, Nat Commun 2014, PMID:24618891. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Bipolar disorder (rs6550435). MyGeneLog™. https://www.mygenelog.com/variants/rs6550435

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