0 111226Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others6Total11Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 15,714 European ancestry cases, 621,182 European ancestry controls, 7,062 East Asian ancestry cases, 195,745 East Asian ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.0871 higher; p = 7 × 10−27.
Where it sits Chromosome 18, band 18q21.1 — in an intron of SMAD7.
What each result means
A/ATwo copies of the version the research linked to Colorectal cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Colorectal cancer. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Colorectal cancer. This is the starting point the study compared everyone against.
Genome medicine · 2024 · PMID 38872215 · open access
Questions about rs6507877
What is rs6507877?
rs6507877 is a single position in the genome, in or near the SMAD7 gene. Published research associates it with colorectal cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6507877 linked to?
On MyGeneLog this position is linked to Colorectal Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs6507877 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6507877 come from?
GWAS Catalog, Genome medicine 2024, PMID:38872215. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 111226Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others6Total11Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Colorectal cancer (rs6507877). MyGeneLog™. https://www.mygenelog.com/variants/rs6507877