Standard
Body mass index
FTO · rs6499640
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Body mass index compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Body mass index.
G/G
Published research associates this genotype with typical/baseline likelihood of Body mass index — no copies of the reported risk allele.
Source
Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity
Thorleifsson G,
Walters GB,
Gudbjartsson DF,
Steinthorsdottir V,
Sulem P,
Helgadottir A,
Styrkarsdottir U,
Gretarsdottir S,
Thorlacius S,
Jonsdottir I,
Jonsdottir T,
Olafsdottir EJ
and 23 more — show all
Olafsdottir GH,
Jonsson T,
Jonsson F,
Borch-Johnsen K,
Hansen T,
Andersen G,
Jorgensen T,
Lauritzen T,
Aben KK,
Verbeek AL,
Roeleveld N,
Kampman E,
Yanek LR,
Becker LC,
Tryggvadottir L,
Rafnar T,
Becker DM,
Gulcher J,
Kiemeney LA,
Pedersen O,
Kong A,
Thorsteinsdottir U,
Stefansson K
Nature genetics · 2009 · PMID 19079260
Questions about rs6499640
What is rs6499640?
rs6499640 is a single position in the genome, in or near the FTO gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs6499640 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6499640 come from?
GWAS Catalog, Nat Genet 2008, PMID:19079260. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants