2 513227123229Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity2Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others29Total51Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 72,598 European ancestry individuals, 1,160 African American individuals; replicated in Up to 11,036 European ancestry individuals, 32,615 individuals.
The effect
Each copy of the A allele shifted the measure 5.25 % SD higher (95% confidence interval 3.82-6.68); p = 4 × 10−13.
How common The A allele had a frequency of about 41% in the people studied.
Where it sits Chromosome 16, band 16q12.2 — in an intron of FTO.
What each result means
A/ATwo copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Body mass index. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs6499640
What is rs6499640?
rs6499640 is a single position in the genome, in or near the FTO gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6499640 linked to?
On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs6499640?
Subjects that appear in the title or abstract of the same papers as this rsID include exercise and muscle (2 papers), cholesterol and blood fats (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs6499640 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6499640 come from?
GWAS Catalog, Nat Genet 2008, PMID:19079260. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 513227123229Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity2Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others29Total51Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Body mass index (rs6499640). MyGeneLog™. https://www.mygenelog.com/variants/rs6499640