Sensitive

3-Indolepropionic acid levels in coronary artery disease

ACSM5 · rs6497488

Where this position leads

Condition: Coronary Artery Disease

rs6497488 Condition: Coronary Artery Disease Coronary Artery Disease Condition rs6497488 rs6497488 ACSM5

What the study found

Who was studied 1,551 Han Chinese ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.4 lower (95% confidence interval 0.28-0.52); p = 6 × 10−11.

How common The T allele had a frequency of about 62% in the people studied.

Where it sits Chromosome 16, band 16p12.3 — in an intron of ACSM5.

What each result means

C/C No copy of the version the research linked to 3-Indolepropionic acid levels in coronary artery disease. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to 3-Indolepropionic acid levels in coronary artery disease. That is a smaller link than two copies.
T/T Two copies of the version the research linked to 3-Indolepropionic acid levels in coronary artery disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6497488

What is rs6497488?

rs6497488 is a single position in the genome, in or near the ACSM5 gene. Published research associates it with 3-indolepropionic acid levels in coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6497488 linked to?

On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs6497488 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6497488 come from?

GWAS Catalog, Clinical and translational medicine 2021, PMID:33634981. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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3-Indolepropionic acid levels in coronary artery disease (rs6497488). MyGeneLog™. https://www.mygenelog.com/variants/rs6497488

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