G/GPublished research associates this genotype with typical/baseline likelihood of Body mass index — no copies of the reported risk allele.
G/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Body mass index.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Body mass index compared to the general population.
Human molecular genetics · 2019 · PMID 30239722 · open access
Questions about rs6497451
What is rs6497451?
rs6497451 is a single position in the genome, in or near the NA gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6497451 linked to?
On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.
Does having rs6497451 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6497451 come from?
GWAS Catalog, Hum Mol Genet 2018, PMID:30239722. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.