Standard

Pulse pressure

PRPH2 · rs649472

Where this position leads

Condition: Blood Pressure

rs649472 Condition: Blood Pressure Blood Pressure Condition rs649472 rs649472 PRPH2

What the study found

Who was studied 80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.203 higher (95% confidence interval -); p = 5 × 10−6.

Where it sits Chromosome 6, band 6p21.1 — in an intron of PRPH2.

What each result means

C/C No copy of the version the research linked to Pulse pressure. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Pulse pressure. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Pulse pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs649472

What is rs649472?

rs649472 is a single position in the genome, in or near the PRPH2 gene. Published research associates it with pulse pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs649472 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs649472 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs649472 come from?

GWAS Catalog, Nat Genet 2016, PMID:27841878. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Pulse pressure (rs649472). MyGeneLog™. https://www.mygenelog.com/variants/rs649472

← See all variants