Body mass index in nulliparous women (aged 20 to <30 years)
MAP2K5 · rs6494678
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 30,272 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.009 lower (95% confidence interval 0.0051-0.0129); p = 2 × 10−8.
How common The T allele had a frequency of about 24% in the people studied.
Where it sits Chromosome 15, band 15q23 — in an intron of MAP2K5.
What each result means
C/CNo copy of the version the research linked to Body mass index in nulliparous women (aged 20 to <30 years). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Body mass index in nulliparous women (aged 20 to <30 years). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Body mass index in nulliparous women (aged 20 to <30 years). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science advances · 2026 · PMID 41564189 · open access
Questions about rs6494678
What is rs6494678?
rs6494678 is a single position in the genome, in or near the MAP2K5 gene. Published research associates it with body mass index in nulliparous women (aged 20 to <30 years). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs6494678 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6494678 come from?
GWAS Catalog, Science advances 2026, PMID:41564189. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 725Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others5Total7Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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Body mass index in nulliparous women (aged 20 to <30 years) (rs6494678). MyGeneLog™. https://www.mygenelog.com/variants/rs6494678