0 223241138Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity0Meta AI4Microsoft · Copilot1Amazon1Apple3China (ByteDance, Huawei, Baidu…)0Others8Total22Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 55,006 British ancestry males, 61,132 British ancestry females; replicated in 112,425 British ancestry males, 133,936 British ancestry females.
The effect
Each copy of the A allele shifted the measure 0.0101 higher; p = 4 × 10−6.
How common The A allele had a frequency of about 22% in the people studied.
Where it sits Chromosome 13, band 13q31.3 — between genes, 6.2 kb from MIR17HG.
What each result means
A/ATwo copies of the version the research linked to Body fat distribution (trunk fat ratio). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Body fat distribution (trunk fat ratio). That is a smaller link than two copies.
C/CNo copy of the version the research linked to Body fat distribution (trunk fat ratio). This is the starting point the study compared everyone against.
Nature communications · 2019 · PMID 30664634 · open access
Questions about rs6492538
What is rs6492538?
rs6492538 is a single position in the genome, in or near the near GPC5 gene. Published research associates it with body fat distribution (trunk fat ratio). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6492538 linked to?
On MyGeneLog this position is linked to Waist-to-Hip Ratio (Body Fat Distribution). The research behind each link, and its sources, are set out on that condition page.
Does having rs6492538 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6492538 come from?
GWAS Catalog, Nat Commun 2019, PMID:30664634. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 223241138Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity0Meta AI4Microsoft · Copilot1Amazon1Apple3China (ByteDance, Huawei, Baidu…)0Others8Total22Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Body fat distribution (trunk fat ratio) (rs6492538). MyGeneLog™. https://www.mygenelog.com/variants/rs6492538