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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,804 European ancestry cases, 2,415 European, South Asian and Hispanic or Latin American ancestry cases, 687,911 European ancestry controls, 477,741 European, South Asian and Hispanic or Latin American ancestry controls.
The effect
Each copy of the T allele carried 1.20 times the odds of COVID-19 (critical illness vs population) (95% confidence interval 1.14-1.25); p = 1 × 10−9.
Where it sits Chromosome 12, band 12q24.13 — in an intron of OAS1.
What each result means
C/CNo copy of the version the research linked to COVID-19 (critical illness vs population). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to COVID-19 (critical illness vs population). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to COVID-19 (critical illness vs population). That is the strongest link of the three results. A link in a study is not a diagnosis.
rs6489867 is a single position in the genome, in or near the OAS1 gene. Published research associates it with covid-19 (critical illness vs population). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs6489867 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6489867 come from?
GWAS Catalog, Nature 2021, PMID:33307546. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
COVID-19 (critical illness vs population) (rs6489867). MyGeneLog™. https://www.mygenelog.com/variants/rs6489867