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Waist-to-hip ratio adjusted for BMI

NRIP3 · rs6486060

What the study found

Who was studied 660,648 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.012 higher (95% confidence interval 0.0083-0.0157); p = 2 × 10−10.

How common The G allele had a frequency of about 45% in the people studied.

Where it sits Chromosome 11, band 11p15.4 — in an intron of NRIP3.

What each result means

A/A No copy of the version the research linked to Waist-to-hip ratio adjusted for BMI. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Waist-to-hip ratio adjusted for BMI. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Waist-to-hip ratio adjusted for BMI. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6486060

What is rs6486060?

rs6486060 is a single position in the genome, in or near the NRIP3 gene. Published research associates it with waist-to-hip ratio adjusted for bmi. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6486060 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6486060 come from?

GWAS Catalog, JAMA 2018, PMID:30575882. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Waist-to-hip ratio adjusted for BMI (rs6486060). MyGeneLog™. https://www.mygenelog.com/variants/rs6486060

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