A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Schizophrenia, bipolar disorder and depression (combined) compared to the general population. (GWAS Catalog, Am J Psychiatry 2010, PMID:20713499)
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Schizophrenia, bipolar disorder and depression (combined). (GWAS Catalog, Am J Psychiatry 2010, PMID:20713499)
G/GPublished research associates this genotype with typical/baseline likelihood of Schizophrenia, bipolar disorder and depression (combined) — no copies of the reported risk allele. (GWAS Catalog, Am J Psychiatry 2010, PMID:20713499)
Source: GWAS Catalog, Am J Psychiatry 2010, PMID:20713499
Questions about rs6484218
What is rs6484218?
rs6484218 is a single position in the genome, in or near the ADM gene. Published research associates it with schizophrenia, bipolar disorder and depression (combined). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6484218 linked to?
On MyGeneLog this position is linked to Bipolar Disorder. The research behind each link, and its sources, are set out on that condition page.
Does having rs6484218 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6484218 come from?
GWAS Catalog, Am J Psychiatry 2010, PMID:20713499. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.