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Hypogonadism

JMJD1C · rs6479897

What the study found

Who was studied 27,736 African American or Afro-Caribbean males.

The effect Each copy of the T allele shifted the measure 0.11 lower (95% confidence interval 0.075-0.145); p = 4 × 10−11.

Where it sits Chromosome 10, band 10q21.3 — in an intron of JMJD1C.

What each result means

C/C No copy of the version the research linked to Hypogonadism. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Hypogonadism. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Hypogonadism. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6479897

What is rs6479897?

rs6479897 is a single position in the genome, in or near the JMJD1C gene. Published research associates it with hypogonadism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6479897 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6479897 come from?

GWAS Catalog, Nature communications 2025, PMID:40316537. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hypogonadism (rs6479897). MyGeneLog™. https://www.mygenelog.com/variants/rs6479897

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