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Who was studied up to 309,889 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0194 lower (95% confidence interval -); p = 5 × 10−12.
How common The T allele had a frequency of about 63% in the people studied.
Where it sits Chromosome 9, band 9q31.3 — between genes, 1.4 kb from EPB41L4B.
What each result means
C/CNo copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
PLoS genetics · 2015 · PMID 26426971 · open access
Questions about rs6477694
What is rs6477694?
rs6477694 is a single position in the genome, in or near the near EPB41L4B gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6477694 linked to?
On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.
Does having rs6477694 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6477694 come from?
GWAS Catalog, PLoS Genet 2015, PMID:26426971. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 2611812319Reads by AI crawlersClaude0ChatGPT0Google · Gemini1Perplexity1Meta AI8Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others9Total26Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Body mass index (rs6477694). MyGeneLog™. https://www.mygenelog.com/variants/rs6477694