A/APublished research associates this genotype with typical/baseline likelihood of Major depressive disorder — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2016, PMID:27479909)
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Major depressive disorder. (GWAS Catalog, Nat Genet 2016, PMID:27479909)
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Major depressive disorder compared to the general population. (GWAS Catalog, Nat Genet 2016, PMID:27479909)
rs6476606 is a single position in the genome, in or near the PAX5 gene. Published research associates it with major depressive disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6476606 linked to?
On MyGeneLog this position is linked to Major Depressive Disorder. The research behind each link, and its sources, are set out on that condition page.
Does having rs6476606 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6476606 come from?
GWAS Catalog, Nat Genet 2016, PMID:27479909. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.