Standard

Gestational duration

GDAP1 · rs6472846

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 195,555 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.351 days lower (95% confidence interval 0.26-0.44); p = 1 × 10⁻¹³.

How common The G allele had a frequency of about 58% in the people studied.

Where it sits Chromosome 8, band 8q21.11 — inside GDAP1.

What each result means

C/C No copy of the version the research linked to Gestational duration. This is the starting point the study compared everyone against.

C/G One copy of the version the research linked to Gestational duration. That is a smaller link than two copies.

G/G Two copies of the version the research linked to Gestational duration. That is the strongest link of the three results. A link in a study is not a diagnosis.

Source

Genetic effects on the timing of parturition and links to fetal birth weight

Solé-Navais P, Flatley C, Steinthorsdottir V, Vaudel M, Juodakis J, Chen J, Laisk T, LaBella AL, Westergaard D, Bacelis J, Brumpton B, Skotte L

and 73 more — show all

Borges MC, Helgeland Ø, Mahajan A, Wielscher M, Lin F, Briggs C, Wang CA, Moen GH, Beaumont RN, Bradfield JP, Abraham A, Thorleifsson G, Gabrielsen ME, Ostrowski SR, Modzelewska D, Nohr EA, Hypponen E, Srivastava A, Talbot O, Allard C, Williams SM, Menon R, Shields BM, Sveinbjornsson G, Xu H, Melbye M, Lowe W Jr, Bouchard L, Oken E, Pedersen OB, Gudbjartsson DF, Erikstrup C, Sørensen E, Lie RT, Teramo K, Hallman M, Juliusdottir T, Hakonarson H, Ullum H, Hattersley AT, Sletner L, Merialdi M, Rifas-Shiman SL, Steingrimsdottir T, Scholtens D, Power C, West J, Nyegaard M, Capra JA, Skogholt AH, Magnus P, Andreassen OA, Thorsteinsdottir U, Grant SFA, Qvigstad E, Pennell CE, Hivert MF, Hayes GM, Jarvelin MR, McCarthy MI, Lawlor DA, Nielsen HS, Mägi R, Rokas A, Hveem K, Stefansson K, Feenstra B, Njolstad P, Muglia LJ, Freathy RM, Johansson S, Zhang G, Jacobsson B

Early Growth Genetics Consortium · Estonian Biobank Research Team · Danish Blood Donor Study Genomic Consortium

Nature genetics · 2023 · PMID 37012456 · open access

Questions about rs6472846

What is rs6472846?

rs6472846 is a single position in the genome, in or near the GDAP1 gene. Published research associates it with gestational duration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6472846 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6472846 come from?

GWAS Catalog, Nature genetics 2023, PMID:37012456. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Gestational duration (rs6472846). MyGeneLog™. https://www.mygenelog.com/variants/rs6472846

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