Standard

Hypo-HDL-cholesterolemia

near KLF14 · rs6467314

Where this position leads

Condition: Hypo-HDL-Cholesterolemia

rs6467314 Condition: Hypo-HDL-Cholesterolemia Hypo-HDL-Cholesterolemia Condition rs6467314 rs6467314 near KLF14

What the study found

Who was studied 10,284 Korean ancestry female cases, 20,929 Korean ancestry female controls.

The effect The reported allele is C; the catalogue records no effect size ; p = 5 × 10−8.

Where it sits Chromosome 7, band 7q32.2 — between genes, 23.2 kb from KLF14.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hypo-HDL-cholesterolemia compared to the general population.
C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hypo-HDL-cholesterolemia.
G/G Published research associates this genotype with typical/baseline likelihood of Hypo-HDL-cholesterolemia — no copies of the reported risk allele.
Source

Questions about rs6467314

What is rs6467314?

rs6467314 is a single position in the genome, in or near the near KLF14 gene. Published research associates it with hypo-hdl-cholesterolemia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6467314 linked to?

On MyGeneLog this position is linked to Hypo-HDL-Cholesterolemia. The research behind each link, and its sources, are set out on that condition page.

Does having rs6467314 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6467314 come from?

GWAS Catalog, International journal of molecular sciences 2022, PMID:36233190. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hypo-HDL-cholesterolemia (rs6467314). MyGeneLog™. https://www.mygenelog.com/variants/rs6467314

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