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Electrocardiogram morphology (amplitude at temporal datapoints)

GPNMB · rs6461703

What the study found

Who was studied 63,706 European and unknown ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0343 lower (95% confidence interval 0.023-0.045); p = 3 × 10−9.

How common The T allele had a frequency of about 58% in the people studied.

Where it sits Chromosome 7, band 7p15.3 — between genes, 11.3 kb from GPNMB.

What each result means

G/G No copy of the version the research linked to Electrocardiogram morphology (amplitude at temporal datapoints). This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Electrocardiogram morphology (amplitude at temporal datapoints). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Electrocardiogram morphology (amplitude at temporal datapoints). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6461703

What is rs6461703?

rs6461703 is a single position in the genome, in or near the GPNMB gene. Published research associates it with electrocardiogram morphology (amplitude at temporal datapoints). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6461703 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6461703 come from?

GWAS Catalog, Cell systems 2020, PMID:32916098. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Electrocardiogram morphology (amplitude at temporal datapoints) (rs6461703). MyGeneLog™. https://www.mygenelog.com/variants/rs6461703

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