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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 30,352 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0613 SD units lower (95% confidence interval 0.044-0.079); p = 1 × 10−11.
How common The T allele had a frequency of about 72% in the people studied.
Where it sits Chromosome 6, band 6p12.2 — in an intron of EFHC1.
What each result means
C/CNo copy of the version the research linked to Eosinophil forward scatter. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Eosinophil forward scatter. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Eosinophil forward scatter. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2023 · PMID 37596262 · open access
Questions about rs6458843
What is rs6458843?
rs6458843 is a single position in the genome, in or near the EFHC1 gene. Published research associates it with eosinophil forward scatter. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs6458843 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6458843 come from?
GWAS Catalog, Nature communications 2023, PMID:37596262. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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