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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 438,351 Non-Finnish European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0171 lower (95% confidence interval 0.013-0.021); p = 9 × 10−18.
How common The C allele had a frequency of about 50% in the people studied.
Where it sits Chromosome 4, band 4p11 — in an intron of FRYL.
What each result means
C/CTwo copies of the version the research linked to Telomere length (principal component 1). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Telomere length (principal component 1). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Telomere length (principal component 1). This is the starting point the study compared everyone against.
Nature genetics · 2024 · PMID 39192095 · open access
Questions about rs6447651
What is rs6447651?
rs6447651 is a single position in the genome, in or near the FRYL gene. Published research associates it with telomere length (principal component 1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs6447651 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6447651 come from?
GWAS Catalog, Nature genetics 2024, PMID:39192095. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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