Standard

Aspirin hydrolysis (plasma)

BCHE · rs6445035

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Aspirin hydrolysis (plasma) compared to the general population.

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Aspirin hydrolysis (plasma).

G/G Published research associates this genotype with typical/baseline likelihood of Aspirin hydrolysis (plasma) — no copies of the reported risk allele.

Source

Aspirin hydrolysis in plasma is a variable function of butyrylcholinesterase and platelet-activating factor acetylhydrolase 1b2 (PAFAH1b2)

Zhou G, Marathe GK, Hartiala J, Hazen SL, Allayee H, Tang WH, McIntyre TM

The Journal of biological chemistry · 2013 · PMID 23508960

Questions about rs6445035

What is rs6445035?

rs6445035 is a single position in the genome, in or near the BCHE gene. Published research associates it with aspirin hydrolysis (plasma). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6445035 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6445035 come from?

GWAS Catalog, J Biol Chem 2013, PMID:23508960. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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