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Systolic blood pressure

MAP4 · rs6442094

Where this position leads

Condition: Blood Pressure

rs6442094 Condition: Blood Pressure Blood Pressure Condition rs6442094 rs6442094 MAP4

What the study found

Who was studied 526,001 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.339 lower (95% confidence interval 0.26-0.41); p = 2 × 10−18.

Where it sits Chromosome 3, band 3p21.31 — in an intron of MAP4.

What each result means

C/C Two copies of the version the research linked to Systolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Systolic blood pressure. That is a smaller link than two copies.
G/G No copy of the version the research linked to Systolic blood pressure. This is the starting point the study compared everyone against.
Source

Questions about rs6442094

What is rs6442094?

rs6442094 is a single position in the genome, in or near the MAP4 gene. Published research associates it with systolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6442094 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs6442094 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6442094 come from?

GWAS Catalog, Investigative ophthalmology & visual science 2022, PMID:35762941. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Systolic blood pressure (rs6442094). MyGeneLog™. https://www.mygenelog.com/variants/rs6442094

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