R3HDM1 · rs6430580
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 35,474 European ancestry uterine leiomyomata cases, 267,505 European ancestry controls, 201,323 European ancestry individuals with age at natural menopause measurements.
The effect The reported allele is A; the catalogue records no effect size ; p = 2 × 10−11.
Where it sits Chromosome 2, band 2q21.3 — in an intron of R3HDM1.
rs6430580 is a single position in the genome, in or near the R3HDM1 gene. Published research associates it with age at natural menopause or uterine leiomyomata (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, American journal of obstetrics and gynecology 2024, PMID:38191017. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Age at natural menopause or uterine leiomyomata (pleiotropy) (rs6430580). MyGeneLog™. https://www.mygenelog.com/variants/rs6430580