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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 113,769 British ancestry cases, 208,811 British ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.0065 higher (95% confidence interval 0.0041-0.0089); p = 4 × 10−8.
How common The A allele had a frequency of about 49% in the people studied.
Where it sits Chromosome 1, band 1p31.1 — between genes, 6.5 kb from RN7SKP19.
What each result means
A/ATwo copies of the version the research linked to Depression (broad). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Depression (broad). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Depression (broad). This is the starting point the study compared everyone against.
Nature communications · 2018 · PMID 29662059 · open access
Questions about rs6424532
What is rs6424532?
rs6424532 is a single position in the genome, in or near the near RN7SKP19 gene. Published research associates it with depression (broad). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs6424532 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6424532 come from?
GWAS Catalog, Nature communications 2018, PMID:29662059. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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