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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 33,748 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 6.72 z score higher; p = 2 × 10−11.
How common The G allele had a frequency of about 49% in the people studied.
Where it sits Chromosome 5, band 5q21.3 — in an intron of EFNA5.
What each result means
A/ANo copy of the version the research linked to Vertex-wise sulcal depth. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Vertex-wise sulcal depth. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Vertex-wise sulcal depth. That is the strongest link of the three results. A link in a study is not a diagnosis.
Science advances · 2021 · PMID 34910505 · open access
Questions about rs641406
What is rs641406?
rs641406 is a single position in the genome, in or near the EFNA5 gene. Published research associates it with vertex-wise sulcal depth. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs641406 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs641406 come from?
GWAS Catalog, Science advances 2021, PMID:34910505. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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