Standard

Age at menopause

near SLC26A8 · rs638600

Where this position leads

Condition: Age at Menopause

rs638600 Condition: Age at Menopause Age at Menopause Condition rs638600 rs638600 near SLC26A8

What the study found

Who was studied 181,219 European ancestry individuals, 43,861 East Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.11 lower; p = 4 × 10−15.

How common The A allele had a frequency of about 62% in the people studied.

Where it sits Chromosome 6, band 6p21.31 — between genes, 5.3 kb from SLC26A8.

What each result means

A/A Two copies of the version the research linked to Age at menopause. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Age at menopause. That is a smaller link than two copies.
G/G No copy of the version the research linked to Age at menopause. This is the starting point the study compared everyone against.
Source

Questions about rs638600

What is rs638600?

rs638600 is a single position in the genome, in or near the near SLC26A8 gene. Published research associates it with age at menopause. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs638600 linked to?

On MyGeneLog this position is linked to Age at Menopause. The research behind each link, and its sources, are set out on that condition page.

Does having rs638600 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs638600 come from?

GWAS Catalog, The Journal of clinical endocrinology and metabolism 2021, PMID:34050765. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Age at menopause (rs638600). MyGeneLog™. https://www.mygenelog.com/variants/rs638600

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