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Photoreceptor cell layer thickness phenotypes (MTAG)

MAP1B · rs63338061

What the study found

Who was studied 31,135 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.07 higher (95% confidence interval 0.05-0.09); p = 1 × 10−10.

How common The T allele had a frequency of about 36% in the people studied.

Where it sits Chromosome 5, band 5q13.2 — in an intron of MAP1B.

What each result means

C/C No copy of the version the research linked to Photoreceptor cell layer thickness phenotypes (MTAG). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Photoreceptor cell layer thickness phenotypes (MTAG). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Photoreceptor cell layer thickness phenotypes (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs63338061

What is rs63338061?

rs63338061 is a single position in the genome, in or near the MAP1B gene. Published research associates it with photoreceptor cell layer thickness phenotypes (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs63338061 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs63338061 come from?

GWAS Catalog, PLoS genetics 2023, PMID:36848389. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Photoreceptor cell layer thickness phenotypes (MTAG) (rs63338061). MyGeneLog™. https://www.mygenelog.com/variants/rs63338061

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