Sensitive

Schizophrenia

HIST1H2APS2 · rs629444

Where this position leads

Condition: Schizophrenia

rs629444 Condition: Schizophrenia Schizophrenia Condition rs629444 rs629444 HIST1H2APS2

What the study found

Who was studied 14,023 East Asian ancestry cases, 33,640 European ancestry cases, 31,505 East Asian ancestry controls, 43,456 European ancestry controls.

The effect Each copy of the C allele carried 1.14 times the odds of Schizophrenia (95% confidence interval 1.11-1.18); p = 2 × 10−13.

Where it sits Chromosome 6, band 6p22.2 — in a non-coding transcript of H2BP5.

What each result means

C/C Two copies of the version the research linked to Schizophrenia. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Schizophrenia. That is a smaller link than two copies.
T/T No copy of the version the research linked to Schizophrenia. This is the starting point the study compared everyone against.
Source

Questions about rs629444

What is rs629444?

rs629444 is a single position in the genome, in or near the HIST1H2APS2 gene. Published research associates it with schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs629444 linked to?

On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.

Does having rs629444 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs629444 come from?

GWAS Catalog, Schizophr Bull 2018, PMID:30285260. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Schizophrenia (rs629444). MyGeneLog™. https://www.mygenelog.com/variants/rs629444

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